Computational Biology
It is an interdisciplinary field that allows to describe, manage, and modelling (in silicio) biological Systems, through the techniques of computer science, applied mathematics and statistics.
The focus lies on developing mathematical modeling and computational simulation techniques. By these means it addresses scientific research topics with their theoretical and experimental questions without a laboratory.
In this field, my attention was mainly focused on the implementation of an analyzer for complex data deriving from biologica systems simulations. This tool, developed during my experience at the Microsoft Research Centre of Trento (CoSBi), was named Snazer.
Snazer
is designed to aid the processes of visualizing and manipulating reactive
models, as well as to share and interpret time-course data produced by
stochastic simulators or by any other means. It loads biological networks
encoded in SBML as well, and stores graph layouts in standard
GraphML files. Moreover, it loads time-course data exported in CSV,
compresses and prepares them for remote sharing and statistical processing.
Finally, to enhance interoperability, it has been equipped with a public,
XML-based, schema to allow other tools both to encapsulate and structure
their time-course data and to package their interaction networks (see the
CoSBi
Web page for Snazer).
Contacts
Address: Dipartimento di Informatica ed Applicazioni "R. M. Capocelli"
Università degli Studi di Salerno
Via Ponte don Melillo - 84084 Fisciano, Salerno (Italy).
email: iaccarino[@]dia[.]unisa[.]it (without [] antispam)